MaghrebDataLibMedV2, Main, Exploration, bibRecord, 000206

The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility

Identifieur interne : 000206 ( Main/Exploration ); précédent : 000205; suivant : 000207

The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility

Auteurs : Hicham Charoute [Maroc] ; Halima Nahili [Maroc] ; Omar Abidi [Maroc] ; Khalid Gabi [Maroc] ; Hassan Rouba [Maroc] ; Malika Fakiri [Maroc] ; Abdelhamid Barakat [Maroc]

Source :

European Journal of Human Genetics [ 1018-4813 ] ; 2013.

RBID : PMC:3925278

Descripteurs français

KwdFr :
- Bases de données génétiques (MeSH), Humains (MeSH), Maladies génétiques congénitales (génétique), Maroc (MeSH), Polymorphisme génétique (MeSH), Prédisposition génétique à une maladie (MeSH).
MESH :
- génétique : Maladies génétiques congénitales.
- Bases de données génétiques, Humains, Maroc, Polymorphisme génétique, Prédisposition génétique à une maladie.
Wicri :
- geographic : Maroc.

English descriptors

KwdEn :
- Databases, Genetic (MeSH), Genetic Diseases, Inborn (genetics), Genetic Predisposition to Disease (MeSH), Humans (MeSH), Morocco (MeSH), Polymorphism, Genetic (MeSH).
MESH :
- geographic : Morocco.
- genetics : Genetic Diseases, Inborn.
- Databases, Genetic, Genetic Predisposition to Disease, Humans, Polymorphism, Genetic.

Abstract

National and ethnic mutation databases provide comprehensive information about genetic variations reported in a population or an ethnic group. In this paper, we present the Moroccan Genetic Disease Database (MGDD), a catalogue of genetic data related to diseases identified in the Moroccan population. We used the PubMed, Web of Science and Google Scholar databases to identify available articles published until April 2013. The Database is designed and implemented on a three-tier model using Mysql relational database and the PHP programming language. To date, the database contains 425 mutations and 208 polymorphisms found in 301 genes and 259 diseases. Most Mendelian diseases in the Moroccan population follow autosomal recessive mode of inheritance (74.17%) and affect endocrine, nutritional and metabolic physiology. The MGDD database provides reference information for researchers, clinicians and health professionals through a user-friendly Web interface. Its content should be useful to improve researches in human molecular genetics, disease diagnoses and design of association studies. MGDD can be publicly accessed at http://mgdd.pasteur.ma.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925278

DOI: 10.1038/ejhg.2013.151
PubMed: 23860041
PubMed Central: 3925278

Affiliations:

Maroc

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility</title>
<author><name sortKey="Charoute, Hicham" sort="Charoute, Hicham" uniqKey="Charoute H" first="Hicham" last="Charoute">Hicham Charoute</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Laboratoire d'Agroalimentaire et Santé, Faculté des Sciences et Techniques, Université Hassan I</institution>
, Settat,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nahili, Halima" sort="Nahili, Halima" uniqKey="Nahili H" first="Halima" last="Nahili">Halima Nahili</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Abidi, Omar" sort="Abidi, Omar" uniqKey="Abidi O" first="Omar" last="Abidi">Omar Abidi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gabi, Khalid" sort="Gabi, Khalid" uniqKey="Gabi K" first="Khalid" last="Gabi">Khalid Gabi</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Département Informatique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rouba, Hassan" sort="Rouba, Hassan" uniqKey="Rouba H" first="Hassan" last="Rouba">Hassan Rouba</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fakiri, Malika" sort="Fakiri, Malika" uniqKey="Fakiri M" first="Malika" last="Fakiri">Malika Fakiri</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Laboratoire d'Agroalimentaire et Santé, Faculté des Sciences et Techniques, Université Hassan I</institution>
, Settat,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barakat, Abdelhamid" sort="Barakat, Abdelhamid" uniqKey="Barakat A" first="Abdelhamid" last="Barakat">Abdelhamid Barakat</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23860041</idno>
<idno type="pmc">3925278</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925278</idno>
<idno type="RBID">PMC:3925278</idno>
<idno type="doi">10.1038/ejhg.2013.151</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">000000</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000000</idno>
<idno type="wicri:Area/Pmc/Curation">000000</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000000</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000270</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000270</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:23860041</idno>
<idno type="wicri:Area/PubMed/Corpus">000612</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000612</idno>
<idno type="wicri:Area/PubMed/Curation">000608</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000608</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000561</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000561</idno>
<idno type="wicri:Area/Main/Merge">000206</idno>
<idno type="wicri:Area/Main/Curation">000206</idno>
<idno type="wicri:Area/Main/Exploration">000206</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility</title>
<author><name sortKey="Charoute, Hicham" sort="Charoute, Hicham" uniqKey="Charoute H" first="Hicham" last="Charoute">Hicham Charoute</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Laboratoire d'Agroalimentaire et Santé, Faculté des Sciences et Techniques, Université Hassan I</institution>
, Settat,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Nahili, Halima" sort="Nahili, Halima" uniqKey="Nahili H" first="Halima" last="Nahili">Halima Nahili</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Abidi, Omar" sort="Abidi, Omar" uniqKey="Abidi O" first="Omar" last="Abidi">Omar Abidi</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Gabi, Khalid" sort="Gabi, Khalid" uniqKey="Gabi K" first="Khalid" last="Gabi">Khalid Gabi</name>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Département Informatique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Rouba, Hassan" sort="Rouba, Hassan" uniqKey="Rouba H" first="Hassan" last="Rouba">Hassan Rouba</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Fakiri, Malika" sort="Fakiri, Malika" uniqKey="Fakiri M" first="Malika" last="Fakiri">Malika Fakiri</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Laboratoire d'Agroalimentaire et Santé, Faculté des Sciences et Techniques, Université Hassan I</institution>
, Settat,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Barakat, Abdelhamid" sort="Barakat, Abdelhamid" uniqKey="Barakat A" first="Abdelhamid" last="Barakat">Abdelhamid Barakat</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Laboratoire de Génétique Moléculaire Humaine, Département de Recherche Scientifique, Institut Pasteur du Maroc</institution>
, Casablanca,<country>Morocco</country>
</nlm:aff>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">European Journal of Human Genetics</title>
<idno type="ISSN">1018-4813</idno>
<idno type="eISSN">1476-5438</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Databases, Genetic (MeSH)</term>
<term>Genetic Diseases, Inborn (genetics)</term>
<term>Genetic Predisposition to Disease (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Morocco (MeSH)</term>
<term>Polymorphism, Genetic (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Bases de données génétiques (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Maladies génétiques congénitales (génétique)</term>
<term>Maroc (MeSH)</term>
<term>Polymorphisme génétique (MeSH)</term>
<term>Prédisposition génétique à une maladie (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Morocco</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genetic Diseases, Inborn</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Maladies génétiques congénitales</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Databases, Genetic</term>
<term>Genetic Predisposition to Disease</term>
<term>Humans</term>
<term>Polymorphism, Genetic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Bases de données génétiques</term>
<term>Humains</term>
<term>Maroc</term>
<term>Polymorphisme génétique</term>
<term>Prédisposition génétique à une maladie</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Maroc</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>National and ethnic mutation databases provide comprehensive information about genetic variations reported in a population or an ethnic group. In this paper, we present the Moroccan Genetic Disease Database (MGDD), a catalogue of genetic data related to diseases identified in the Moroccan population. We used the PubMed, Web of Science and Google Scholar databases to identify available articles published until April 2013. The Database is designed and implemented on a three-tier model using Mysql relational database and the PHP programming language. To date, the database contains 425 mutations and 208 polymorphisms found in 301 genes and 259 diseases. Most Mendelian diseases in the Moroccan population follow autosomal recessive mode of inheritance (74.17%) and affect endocrine, nutritional and metabolic physiology. The MGDD database provides reference information for researchers, clinicians and health professionals through a user-friendly Web interface. Its content should be useful to improve researches in human molecular genetics, disease diagnoses and design of association studies. MGDD can be publicly accessed at <ext-link ext-link-type="uri" xlink:href="http://mgdd.pasteur.ma">http://mgdd.pasteur.ma</ext-link>
.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Maroc</li>
</country>
</list>
<tree><country name="Maroc"><noRegion><name sortKey="Charoute, Hicham" sort="Charoute, Hicham" uniqKey="Charoute H" first="Hicham" last="Charoute">Hicham Charoute</name>
</noRegion>
<name sortKey="Abidi, Omar" sort="Abidi, Omar" uniqKey="Abidi O" first="Omar" last="Abidi">Omar Abidi</name>
<name sortKey="Barakat, Abdelhamid" sort="Barakat, Abdelhamid" uniqKey="Barakat A" first="Abdelhamid" last="Barakat">Abdelhamid Barakat</name>
<name sortKey="Charoute, Hicham" sort="Charoute, Hicham" uniqKey="Charoute H" first="Hicham" last="Charoute">Hicham Charoute</name>
<name sortKey="Fakiri, Malika" sort="Fakiri, Malika" uniqKey="Fakiri M" first="Malika" last="Fakiri">Malika Fakiri</name>
<name sortKey="Gabi, Khalid" sort="Gabi, Khalid" uniqKey="Gabi K" first="Khalid" last="Gabi">Khalid Gabi</name>
<name sortKey="Nahili, Halima" sort="Nahili, Halima" uniqKey="Nahili H" first="Halima" last="Nahili">Halima Nahili</name>
<name sortKey="Rouba, Hassan" sort="Rouba, Hassan" uniqKey="Rouba H" first="Hassan" last="Rouba">Hassan Rouba</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/MaghrebDataLibMedV2/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000206 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000206 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    MaghrebDataLibMedV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3925278
   |texte=   The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:23860041" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a MaghrebDataLibMedV2

This area was generated with Dilib version V0.6.38.
Data generation: Wed Jun 30 18:27:05 2021. Site generation: Wed Jun 30 18:34:21 2021

Serveur sur les données et bibliothèques médicales au Maghreb (version finale)

The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility

The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur sur les données et bibliothèques médicales au Maghreb (version finale)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.